Mets vs. Astros odds, prediction, betting line: 2022 MLB picks, Wednesday, June 22 best bets from proven model

Wednesday afternoon features an intriguing MLB showcase at Minute Maid Park. The Houston Astros host the New York Mets in a battle between division leaders. The matchup serves as the finale of a quick, two-game set between inter-league foes. Houston won the first matchup, improving to 42-25, with New York falling to 45-25 this season.

First pitch is at 2:10 p.m. ET in Houston. Caesars Sportsbook lists Houston as a -140 favorite (risk $140 to win $100) on the money line, while the over-under, or total number of runs Vegas thinks will be scored, is eight in the latest Mets vs. Astros odds. Before you make any Astros vs. Mets picks, you need to see the MLB predictions and betting advice from SportsLine’s advanced computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a strong start to the 2022 season. It’s on a 56-47 roll on top-rated MLB money-line picks through 11 weeks. Anybody who has followed it has seen profitable returns.

Now, the model has set its sights on Mets vs. Astros, and just locked in its picks and MLB predictions. You can head to SportsLine to see its picks. Here are several MLB odds and betting lines for Astros vs. Mets:

  • Mets vs. Astros money line: Astros -140, Mets +120
  • Mets vs. Astros over-under: 8 runs
  • Mets vs. Astros run line: Astros -1.5 (+145)
  • Mets vs. Astros tickets: See tickets at StubHub
  • NYM: The Mets are 20-9 in day games
  • HOU: The Astros are 17-8 in day games

Featured Game | Houston Astros vs. New York Mets

Why you should back the Mets

The Mets are enjoying considerable success in 2022. New York entered the series against Houston with NL-leading marks in runs scored, hits, triples, batting average, and on-base percentage this season. The Mets are also strongly above-average in avoiding strikeouts on offense, and New York’s lineup has been highly productive. 

On the run prevention side, the Mets will deploy Carlos Carrasco as the starting pitcher on Wednesday, and the veteran right-hander has a 3.74 ERA since May 1 and an ERA below 4.00 for the full season. Carrasco is averaging a strikeout per inning, issuing only 1.9 walks per nine innings, and allowing only 0.7 home runs per nine innings this season. Carrasco is backed by an above-average bullpen from a statistical perspective, and he has a 3.69 career ERA in starts against the Astros.

Why you should back the Astros

The Astros are loaded with talent at every level. Houston has one of the best hitters in the game in Yordan Alvarez in the middle of the lineup, and he owns an OPS over 1.000 for the season. Alvarez, combined with a deep and balanced group, leads the Astros to top-five marks in home runs, slugging percentage, walks, strikeout avoidance, and OPS for the season. In addition, Houston is slugging more than .400 as a team in 2022, and run prevention projects well for the Astros on Wednesday. 

The Astros entered the series with the Mets with the best bullpen ERA in the league, and Houston’s relief corps is striking out more than a batter per inning. Before they arrive in the game, Houston starter Luis Garcia provides a high baseline with a career 3.43 ERA and a 3.41 ERA for the 2022 season. Garcia has been even better lately, posting a 3.05 ERA over the last eight weeks, and he owns a 1.03 WHIP in 2022.

How to make Astros vs. Mets picks

SportsLine’s model is leaning over on the total, projecting 9.2 combined runs. It also says one side of the money line has all the value. You can only get the model’s MLB picks at SportsLine.

So who wins Mets vs. Astros? And which side has all the value? Visit SportsLine now to which side of Astros vs. Mets you need to jump on Wednesday, all from the model that has crushed its MLB picks, and find out. 

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