Paul previously defeated fellow YouTube personality AnEsonGib, former NBA star Nate Robinson and former MMA fighter Ben Askren.
The pay-per-view event, which includes five fights, is scheduled to start Sunday, August 29 at 8 p.m. ET at the Rocket Mortgage FieldHouse in Cleveland, Ohio.
The 8-round cruiserweight bout will be available on Showtime, with general tickets available for $59.99.
Before turning toward a boxing career, Paul had been widely known on social media as a brash and controversial YouTube star, where he has more than 20 million subscribers.
“In 4 days I fight for more than what’s at the surface level,” Paul said in an Instagram post Wednesday. “I fight for my family, my friends, my coaches, my city, my dog, for shadow, for history, a greater purpose, and for respect. Sunday August 29th the world will see what I’m made of.”
The event includes an undercard featuring Amanda Serrano against Yamileth Mercado, Daniel Dubois versus Joe Cusumano, Ivan Baranchyk against Montana Love and Tommy Fury versus Anthony Taylor.
The two groups had to be separated, according to ESPN, following “heating, vulgar language” and “a lot of pushing and shoving.”