Cubs vs. Pirates odds, line: 2021 MLB picks, Sept. 3 predictions from proven computer model

The Chicago Cubs will look to continue their season-long dominance of the Pittsburgh Pirates when they meet in the second of a four-game series on Friday. The Cubs (60-75), who are fourth in the National League Central Division, are 34-32 at home this season. The Pirates (48-86), fifth in the division, have struggled on the road, going 20-48. The Cubs have won five of the seven meetings with Pittsburgh at Wrigley Field this year.

The game is slated to begin at 2:20 p.m. ET from Chicago. Pittsburgh is 27th in MLB in team batting average at .233, while Chicago is 28th at .230. The Cubs are -135 favorites (risk $135 to win $100) on the money line in the latest Pirates vs. Cubs odds from Caesars Sportsbook, while the over-under for total runs scored is nine. Before making any Cubs vs. Pirates picks, check out the latest MLB predictions from the SportsLine Projection Model.

This model, which simulates every game 10,000 times, is 176-142 on top-rated MLB money-line picks through 22 weeks in the 2021 season, returning almost $1,000. It also had a banner 2019 season, the league’s last full schedule, returning more than $1,400 on its top-rated money-line and run-line picks. Anyone following it has seen some huge returns.

Now, the model has dialed in on Cubs vs. Pirates and revealed its predictions and best bets. You can visit SportsLine now to see its MLB picks. Here are the MLB odds and betting trends for Pirates vs. Cubs:

  • Pirates vs. Cubs money line: Pittsburgh +115, Chicago -135
  • Pirates vs. Cubs run line: Chicago -1.5 (+140)
  • Pirates vs. Cubs over-under: 9 runs
  • PIT: The Pirates are 30-70 in their last 100 games as an underdog
  • CHI: The Cubs are 4-1 in their last five of a Game 2 in a series

Featured Game | Chicago Cubs vs. Pittsburgh Pirates

Why you should back the Cubs

Third baseman Patrick Wisdom is one of Chicago’s most consistent hitters. Wisdom has hits in nine of his last 12 games and is batting .251 with 25 homers, 50 RBIs and 46 runs scored. In last weekend’s series against the Chicago White Sox, Wisdom was 4-for-11 with four homers and six RBIs. He has feasted on Pirates pitching and in three games is hitting .300 with two doubles, homer and one RBI.

Also red hot of late is outfielder Jason Heyward, who has hits in six of his past seven games, including three multi-hit games. This past weekend against the White Sox, Heyward was 5-for-10 with a double and two RBIs. In 10 games against Pittsburgh this season, he has a double, homer and two RBIs. In 131 career games vs. the Pirates, he is batting .294 with 27 doubles, two triples, 11 homers and 61 RBIs.

Why you should back the Pirates

Left-hander Steven Brault (0-3, 4.57 ERA) is expected to take the mound for Pittsburgh. Brault, who is making his sixth start of the year, has allowed two or fewer runs in four of his previous five starts. In a 3-0 loss at St. Louis on Aug. 22, he allowed just one earned run on five hits in four innings. He walked two and struck out one. In 16 career games against the Cubs, including seven starts, Brault is 0-2, giving up 35 earned runs in 48 1/3 innings with 25 walks and 39 strikeouts.

Offensively, the Pirates have been powered by outfielder Bryan Reynolds, who was 2-for-4 in Thursday’s loss to the Cubs. He has hits in eight of his past 11 games. For the season, Reynolds has displayed some pop and is batting .299 with 21 homers, 77 RBIs and 74 runs scored. In 10 games against Chicago in 2021, he is batting .289 (13-for-45) with one double, one homer and three RBIs. 

How to make Pirates vs. Cubs picks

SportsLine’s model is leaning under on the total, as the simulations have the teams combining for 8.8 runs. It also says one side of the money line has all the value. You can only get the pick at SportsLine.

So who wins Pirates vs. Cubs? And which side of the money line has all the value? Visit SportsLine now to see which side to back, all from the advanced model that’s on a roll on its MLB picks, and find out. 

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