MLB

2021 MLB playoffs: Red Sox vs. Astros odds, ALCS Game 4 picks, predictions from proven computer model

The Boston Red Sox will look to take a commanding 3-1 lead when they take on the Houston Astros in Game 4 of the 2021 American League Championship Series on Tuesday. The Red Sox (92-70), who cruised to a 12-3 win on Monday night, have won six of eight games in the 2021 MLB playoffs. The Astros (95-67), meanwhile, have won six of 10 meetings with Boston this season. Houston is looking to earn its third trip to the World Series in five years, while the Red Sox are trying to reach the World Series for the fifth time since 2004. Houston will send Zack Greinke to the mound, while Nick Pivetta gets the start for Boston. 

First pitch from Boston is set for 8:08 p.m. ET. Boston leads the all-time series 41-34. Boston is the -125 favorite (risk $125 to win $100) on the money line in the latest Red Sox vs. Astros odds from Caesars Sportsbook, while the over-under for total runs scored is 10. Before making any Astros vs. Red Sox picks, be sure to see the 2021 MLB playoff predictions and betting advice from SportsLine’s proven computer model

This model, which simulates every game 10,000 times, enters the third week of the 2021 MLB playoffs with a 207-176 record on top-rated MLB money-line picks, returning well over $600. Anyone following it has seen some huge returns.

Now, the model has dialed in on Red Sox vs. Astros and just released its coveted 2021 ALCS picks and predictions. You can visit SportsLine now to see the model’s ALCS picks. Here are the MLB odds and betting lines for Astros vs. Red Sox:

  • Astros vs. Red Sox money line: Houston +115, Boston -125
  • Astros vs. Red Sox run line: Boston -1.5 (+145)
  • Astros vs. Red Sox over-under: 10 runs
  • HOU: The Astros are 4-1 in their last five games after allowing five runs or more in their previous game
  • BOS: The Red Sox are 7-0 in their last six postseason home games

Featured Game | Boston Red Sox vs. Houston Astros

Why you should back the Red Sox

For the second game in a row, Boston’s offense hit Houston pitching hard, including the team’s third grand slam homer of the series. This time it was Kyle Schwarber who went deep to all but seal the Red Sox’s Game 3 win. Schwarber has hits in all three games of the series, including a double and a grand slam homer. He is 9-for-32 (.281) in the postseason with three homers and six RBIs.

Also continuing his torrid hitting is designated hitter J.D. Martinez, who is 4-for-11 in the series, including a first-inning grand slam in Game 2. He is hitting .364 in the series and has hits in five of the last six games, including a four-hit performance at Tampa Bay on Oct. 8. He batted .286 during the regular season with 28 homers, 99 RBIs and 92 runs scored. In 45 career games against Houston, he is hitting .241 with eight doubles, nine homers and 29 RBIs.

Why you should back the Astros 

Outfielder Kyle Tucker provided Houston’s offense in Game 3 with a fourth-inning three-run home run. He is hitting .300 for the series, including a 2-for-4 performance in Game 2. He is 8-for-27 (.296) with two doubles, three homers and 11 RBIs this postseason. For the season, Tucker hit .294 with 30 homers, 92 RBIs and 83 runs scored. In nine career games against Boston, Tucker is 15-for-35 (.429) with seven doubles, one homer and 11 RBIs.

First baseman Yuli Gurriel has been red hot in the series, going 5-for-10 with a homer and three RBIs. He was 2-for-3 in Game 3 and has a four-game hitting streak this postseason. He has hit Boston hard this season, going 14-for-31 (.452) with a double, three home runs and nine RBIs in nine games. During the regular season, Gurriel batted .319 with 15 homers, 81 RBIs and 83 runs scored.

How to make Red Sox vs. Astros ALCS picks

The model is leaning over on the total, projecting 10.4 combined runs. It also says one side of the money line has all the value. Head to SportsLine now to see its MLB picks

So who wins Game 4 of Astros vs. Red Sox in the ALCS 2021? And which side of the money line has all the value? Visit SpotsLine now to see which side to jump on, all from the model that has crushed its MLB picks, and find out. 



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