2021 MLB playoffs: Red Sox vs. Astros odds, ALCS Game 2 picks, predictions from proven computer model

The Houston Astros look to take command of the 2021 American League Championship Series when they face the Boston Red Sox in Game 2 on Saturday afternoon. The Astros (95-67), who won the AL West by five games over the Seattle Mariners, have dominated the Red Sox (92-70) this season, winning six of eight meetings, including a 5-4 win in Game 1 on Friday. Boston, which placed second in the AL East, is coming off a 3-1 series victory over the 100-win Tampa Bay Rays. Including Game 1, the Astros have won four of the five games played in Houston against the Red Sox in 2021.

First pitch from Minute Maid Park in Houston is set for 4:20 p.m. ET. Boston leads the all-time series 39-34, although the series is tied 19-19 in games played at Houston. Houston is a -130 favorite (risk $130 to win $100) on the money line in the latest Red Sox vs. Astros odds from Caesars Sportsbook, while the over-under for total runs scored is 8.5. Before making any Astros vs. Red Sox picks, be sure to see the 2021 MLB playoff predictions and betting advice from SportsLine’s proven computer model

This model, which simulates every game 10,000 times, enters the second week of the 2021 MLB playoffs with a 207-175 record on top-rated MLB money-line picks, returning well over $700. It also had a banner 2019 season, the league’s last full schedule, returning more than $1,400 on its top-rated money-line and run-line MLB picks. Anyone following it has seen some huge returns.

Now, the model has dialed in on Red Sox vs. Astros and just released its coveted 2021 American League Championship Series picks and predictions. You can visit SportsLine now to see the model’s ALCS picks. Here are the MLB odds and betting lines for Red Sox vs. Astros:

  • Red Sox vs. Astros money line: Boston +120, Houston -130
  • Red Sox vs. Astros run line: Houston -1.5 (+145)
  • Red Sox vs. Astros over-under: 8.5 runs
  • BOS: The Red Sox are 4-1 in their last five league championship games
  • HOU: The Astros are 6-1 in their last seven games vs. a team with a winning record

Featured Game | Houston Astros vs. Boston Red Sox

Why you should back the Astros

Houston is expected to send right-hander Luis Garcia (11-8, 3.30 ERA) to the mound. In 28 starts and 30 appearances during the regular season, Garcia allowed just 132 hits in 155 1/3 innings with 50 walks and 167 strikeouts. He has struggled in his last two appearances, but had been sharp in his previous two outings, going 1-0 while allowing just one earned run in 11 1/3 innings in a no-decision against the Los Angeles Angels and a win over the Texas Rangers. He is 1-0 against Boston this season, allowing one earned run and five hits in seven innings. He walked one and struck out six.

Jose Altuve continues his torrid postseason, going 1-for-3 with a homer, three RBIs, one walk and two runs scored in the Game 1 victory over the Red Sox. Altuve hit .313 in the ALDS, including a 3-for-5 performance with a double, home run and three RBIs in the Game 4 clincher over Chicago on Tuesday. He had a .625 slugging percentage against the White Sox. In 48 career regular-season games against the Red Sox, Altuve is batting .327 with 12 doubles, eight homers and 23 RBIs. He has also walked 19 times and stolen 10 bases.

Why you should back the Red Sox

Boston is expected to start right-hander Nathan Eovaldi (11-9, 3.75 ERA). He has been dominant in his last three starts, picking up a pair of wins. Although he got a no-decision in Boston’s 6-4 13-inning win over Tampa Bay in Game 3 of the ALDS, he allowed just two earned runs on three hits in five innings. He walked one and struck out eight. He defeated the New York Yankees 6-2 in the AL Wild Card Game on Oct. 5, allowing one earned run on four hits in 5 1/3 innings. He struck out eight and did not walk a batter. In six career starts against the Astros, Eovaldi is 1-2 with a 3.93 ERA. He’s walked 12, while striking out 33.

Powering Boston’s offense in the Game 1 loss to Houston was center fielder Kike Hernandez, who was 4-for-5 with two home runs. Hernandez has been on fire in the postseason, going 14-for-28 (.500) with four doubles, four homers and eight RBIs. In the 14-6 ALDS Game 2 win over Tampa Bay, he was 5-for-6 with three doubles, one home run, three RBIs and three runs scored. In 16 career games vs. Houston, Hernandez is hitting .264 with four doubles, three homers and six RBIs.

How to make Red Sox vs. Astros ALCS picks

The model is leaning over on the total, projecting 10.2 combined runs. It also says one side of the money line has all the value. Head to SportsLine to see its MLB picks

So who wins Game 2 of Astros vs. Red Sox in the ALCS 2021? And which side of the money line has all the value? Visit SpotsLine now to see which side to jump on, all from the model that has crushed its MLB picks, and find out. 

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